Research topic:

Generation of an ELISA for the protein MIA2 and its validation and evaluation as serological test for hepatic fibrosis

In collaboration with Prof. Anja Bosserhoff we have discovered and characterized MIA2 as novel gene of the MIA gene family. MIA2 is exclusively expressed by hepatocytes.

MIA2 IH

Interestingly, hepatic MIA2 expression correlates significantly with the stage of hepatic fibrosis in patients with different kinds of underlying liver disease.

In a research consortium we are developing an ELISA for the quantification of the protein MIA2 in the serum of patients together with our academic Partner Prof. Anja Bosserhoff and our industrial Partner Scil Proteins.

The project is funded by the German Ministry for Education and Research (BMBF) within the framework Molecular Diagnostics.